IDENTIFICATION OF NOVEL CHEMICAL SCAFFOLDS THAT INHIBIT THE GROWTH OF MYCOBACTERIUM TUBERCULOSIS IN MACROPHAGES

Identification of Novel Chemical Scaffolds that Inhibit the Growth of Mycobacterium tuberculosis in Macrophages

Mycobacterium tuberculosis is an important global pathogen for which new drugs are urgently required.The ability of the organism to survive and multiply within macrophages may contribute to the lengthy treatment regimen with multiple drugs that are required to cure ps5 edmonton in stock the infection.We screened the MyriaScreen II diversity library

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THE PRESENCE OF FEMININE GRAMMATICAL GENDER IN THE NOMINA AGENTIS CATEGORY IN ITALIAN DICTIONARIES DE MAURO AND IL SABATINI COLETTI

This paper aims to examine the relationship between language and gender in the Italian language, with specific reference to the names indicating professions.The work is divided into two parts: in the first part a general picture of the situation is outlined through a synthesis of the most significant academic and institutional contributions in the

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Use of three-dimensional computational fluid dynamics model for a new configuration of circular primary settling tank

Appropriately used, computational fluid dynamics models are powerful tools to design and optimize primary settling tanks (PSTs).This paper uses a Fluent-based 3D model to identify the possible causes for underperformance of the circular PSTs at the Cali waste-water treatment plant, Colombia, and to propose design modifications to improve performanc

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Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

Cellular protein homeostasis (proteostasis) plays an essential role in regulating the folding, sequestration, and turnover of misfolded proteins via a network of chaperones and clearance factors.Previous work has shown that misfolded proteins are spatially sequestered into membrane-less compartments in the cell as part of the proteostasis process.S

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